Aronia, Cognition, and Eye Health (ACE)


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There is great interest in improving cognitive performance and eye health as working from home becomes more prominent. Working from home as well as stress in the workplace is an increasing problem. Students and work professional can therefore benefit from improved attention and thus performance in academic and other work environments. A completely natural supplement with aronia melanocarpa extract could be a promising way to naturally improve cognitive performance

Targeted Conditions

Study Overview

Start Date
December 8, 2022
Completion Date
August 1, 2024
Date Posted
January 12, 2023
Accepts Healthy Volunteers?


Full Address
Maastricht University
Maastricht, Netherlands


Minimum Age (years)
Maximum Age (years)
Eligibility Criteria
Inclusion Criteria:

Healthy men and women, aged between 18-35 years
BMI between 18-30 kg/m2
Systolic blood pressure < 160 mmHg and diastolic blood pressure < 100 mmHg
Stable body weight (weight gain or loss < 3 kg in the past three months)
Willingness to give up being a blood donor from 8 weeks before the start of the study, during the study and for 4 weeks after completion of the study
No difficult venipuncture as evidenced during the screening visit

Exclusion Criteria:

Smoking or smoking cessation < 12 months
Contact lens wearers
Past refractive surgery
Severe medical conditions, including asthma, chronic obstructive pulmonary disease (COPD), kidney failure, auto-inflammatory diseases, rheumatoid arthritis, diabetes mellitus, cardiovascular disease
Use of dietary supplements or medication affecting the main outcomes of the study
Use of an investigational product within another biomedical intervention trial within the previous month
Familial hypercholesterolemia
Abuse of drugs
More than 3 alcoholic consumptions per day

Study Contact Info

Study Contact Name
Sanne Ahles, Msc
Study Contact Email
Study Contact Phone

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Other Details

FDA Regulated Drug?
FDA Regulated Device?
Detailed Description
The shift of on-site education/working to online education/working has had a detrimental impact on motivation to study or work and ultimately on mental health. Moreover, online education has been shown to have a negative effect on concentration, learning, and academic performance. Stress in the workplace is an increasing problem, leading to decreased productivity and overall well-being of working adults. Consequently, there is a great interest in improving cognitive performance, including memory and attention.

Previous studies in young adults have mainly focused on acute or short-term (e.g. 1 week) effects of anthocyanin supplementation on cognitive performance. The research hypothesis of the current study is that long term (6 weeks) AME supplementation affects domains of cognitive performance in a randomized, double-blind, placebo controlled, cross-over study in healthy young adults (18-35 years old).
NCTid (if applicable)