Association Between Postoperative Administration of L-Arginine and CSA-AKI

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Description

To investigate the association between the the early administration of L-Arginine after CPB-assisted cardiac surgery and the incidence of CS-AKI in adult patients. To test if it can reduce the incidence of post-operative AKI.

Targeted Conditions

Study Overview

Start Date
December 1, 2023
Completion Date
March 1, 2024
Enrollment
7000
Date Posted
February 8, 2024
Accepts Healthy Volunteers?
No
Gender
All

Locations

Full Address
Xijing Hospital
Xi'an, Shaanxi 710032, China

Eligibility

Study Population
All patients who were admitted to the ICU after cardiac surgery with CPB.
Minimum Age (years)
18
Eligibility Criteria
Inclusion Criteria:

adult patients (over 18 years)
underwent CPB assisted cardiac surgery
admitted to ICU

Exclusion Criteria:

congenital heart disease
underwent deep hypothermic circulatory arrest (DHCA)
with glomerular filtration rate (eGFR) below 30 mL/min/1.73 m²

Study Contact Info

Study Contact Name
Ziyu Zheng
Study Contact Email
Study Contact Phone

Contact Listings Owner Form

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Other Details

FDA Regulated Drug?
No
FDA Regulated Device?
No
NCTid (if applicable)
NCT06248359