Comparing the effect of Simvastatin versus calcium hydroxide used as an intracanal medicament on Post-operative Pain and Total amount of IL-6 and IL-8 in Periapical Fluids of lower premolars in patients with Symptomatic Apical Periodontitis:
Cairo 52431, Egypt
Patients who are free from any physical or mental handicapping condition with no underlying systemic disease.
Lower single rooted premolars:
Presence of pain with percussion.
Widening in the periodontal membrane space or with small sized periapical radiolucency.
Diagnosed clinically with symptomatic apical periodontitis.
Patients' acceptance to participate in the trial.
Patients who can understand pain scale and can sign the informed consent
Medically compromised patients
Patients who are allergic to non-steroidal anti-inflammatory drugs.
Patients with two or more adjacent teeth requiring root canal therapy
If analgesics or antibiotics have been administrated by the patient during the past 24 hours preoperatively.
Patients reporting bruxism or clenching.
Teeth associated with acute periapical abscess, swelling or a fistulous tract.
Greater than grade I mobility or pocket depth greater than 5mm.
Non restorable teeth.
Teeth with previous endodontic treatment.
Radiographic evidence of external or internal root resorption vertical root fracture, perforation, calcification.
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Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8 0 reviewsWrite Your Review
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