Evaluation of Fluid Responsiveness With Recruitment Maneuver After Sternotomy in Coronary Artery Bypass Surgery

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Description

Assuming that the basic reliability of dynamic indices will increase with the application of functional hemodynamic tests after sternotomy and protective lung ventilation in patients undergoing elective coronary artery bypass surgery, it is useful to predict fluid responsiveness after sternotomy in coronary artery bypass surgery patients ventilated with 6 ml/kg PBW (ideal body weight). We aimed to reveal the sensitivity and specificity of PPV and SVV changes by applying a lung opening maneuver.

Study Overview

Start Date
June 1, 2023
Completion Date
February 20, 2024
Enrollment
45
Date Posted
February 8, 2024
Accepts Healthy Volunteers?
No
Gender
All

Locations

Full Address
Ankara Bilkent Şehir Hastanesi
Ankara 06800, Turkey

Eligibility

Study Population
ASA2-3 patients between the ages of 18-80 who will undergo elective coronary bypass surgery under general anesthesia
Minimum Age (years)
18
Maximum Age (years)
80
Eligibility Criteria
Inclusion Criteria:
1-ASA2-3 patients between the ages of 18-80 who will undergo elective coronary bypass surgery under general anesthesia
Exclusion Criteria:
1. Be younger than 18 years old, be over 80 years old
2. Patients with an ASA score greater than 3
3. EF<40%
4. Those with contraindications to anesthetic drugs
5. Patients with BMI>30
6. Patients who did not want to participate in the study
7. Right ventricular dysfunction
8. COPD(Chronic obstructive pulmonary disease)
9. Bullous lung disease
10. Moderate to severe PHT
11. Severe kidney or liver disease
12. Patients with hemodynamic instability in the perioperative period
13. Pregnancy

Study Contact Info

Study Contact Name
meltem sakman yılmaz
Study Contact Email
Study Contact Phone

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Other Details

FDA Regulated Drug?
No
FDA Regulated Device?
No
Detailed Description
In order to evaluate the fluid deficit in patients undergoing coronary artery bypass surgery, researchers will measure stroke volume index, cardiac index and mean arterial pressure while the patients are in the lima position.

Then researchers will perform a lung opening maneuver (30mmHg for 30 seconds) and measure again.

researchers will measure again after the values return to normal. researchers will give patients balanced fluid at 3ml/kg and record their values.

Can researchers predict fluid response with lung opening maneuver?
NCTid (if applicable)
NCT06249568