Obtain blood samples for generation and maintenance of induced pluripotent stem cells (iPSCs) and genomic/DNA sequencing for biomedical research that will improve the understanding and treatment of pediatric cardiovascular disease
Columbus, Ohio 43205, United States
The subjects must have the diagnosis of cardiovascular disease
The subject must have a syndrome associated with cardiovascular disease
The subject must be related to an individual in cohort 1 or 2
The subject is considered a control and does not fall into any of the other cohorts
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The DNA from these patients will be analyzed for point mutations, rare sequence variations, single nucleotide polymorphisms in known cardiac development genes or for chromosomal copy number changes by using state of the art genetic approaches.