Study of Healthy Cohort for Early Detection of Cancer


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Cancer produces a significant burden on society with a majority diagnosed at late stages when the chance of cure is low. Early diagnosis improves patient outcomes. Data consisting of lifestyle factors, medications, physical activity, years before conventional cancer diagnosis is also worthwhile for to determine early detection. This is only achievable with longitudinal tracking of a large number of healthy individuals and identifying those who do develop cancer over time.

Targeted Conditions

Study Overview

Start Date
February 1, 2023
Completion Date
February 28, 2043
Date Posted
January 14, 2022


Full Address
Johns Hopkins Hospital
Baltimore, Maryland 21205, United States


Study Population
Prospective participants who are to undergo upper or lower gastrointestinal endoscopies as part of their normal medical care and deemed necessary by their physicians
Minimum Age (years)
Eligibility Criteria
Inclusion Criteria:

All adults 18 years of age of older undergoing upper or lower endoscopy for routine medical care.

Exclusion Criteria:

Persons with current malignancy
Persons with history of malignancy and treatment within last 5 years of enrollment, excluding non-melanoma skin cancer or cervical in-situ.
Persons who are unable or unwilling to provide repeat blood samples and complete follow-up questionnaires
Persons who lack the capacity to provide consent
Persons who do not speak English
Persons who are visually or hearing impaired.

Study Contact Info

Study Contact Name
Elham Afghani
Study Contact Email
Study Contact Phone

Contact Listings Owner Form

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Other Details

FDA Regulated Drug?
FDA Regulated Device?
Detailed Description
To conduct a longitudinal cohort study of patients who do not have a malignancy at the time of enrollment and are followed over a 20 year period to see if patients develop a malignancy and associate clinical and lifestyle factors as well as collection of blood. All adults 18 years of age and older undergoing upper or lower endoscopy for routine medical care will be eligible for this study.
NCTid (if applicable)